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(Continued) Copyright © 2005 IOP Publishing Ltd. 1007978-1-60327-489-0_16, 349 Ó Humana Press, Totowa, NJ 2008 Saladin: Anatomy 8.
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Bennett,Phys. 1995). Lenglet S, Louiset E, Delarue C, Vaudry H, Contesse V. 2 Growth Factors of Mammalian Cells Growth Range of Factor Specificity Effects Epidermal growth factor (EGF) Erythropoietin Fibroblast growth factor (FGF) Insulin-like growth factor Interleukin-2 Mitosis-promoting factor (MPF) Nerve growth factor (NGF) Platelet-derived growth factor (PDGF) Transforming growth factor β (TGF-) Broad Stimulates cell proliferation in many tissues; plays a key role in regulating embryonic development Narrow Required for proliferation of red blood cell precursors and their maturation into erythrocytes (red blood cells) Broad Initiates the proliferation of many cell types; inhibits maturation of many types of stem cells; acts as a signal in embryonic development Broad Stimulates metabolism of many cell types; potentiates the effects of other growth factors in promoting cell proliferation Narrow Triggers the division of activated T lymphocytes during the immune response Broad Regulates entrance of the cell cycle into the M phase Narrow Stimulates the growth of neuron processes during miller development Broad Promotes the proliferation of many connective tissues and some neuroglial cells Broad Accentuates or inhibits the responses of many cell types to other growth factors; often plays an important role in cell differentiation 220 Part IV Reproduction and Heredity 10.
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